P. Nakielski, T. Kowalczyk, T.A. Kowalewski
Institute of Fundamental Technological Research Polish Academy of Sciences, Warsaw, Poland
Comprehensive studies of drug transport in nanofibres based mats have been performed to predict drug release kinetics. The paper presents our approach to analyze the impact of fibers arrangement, one of the parameters varied in our parallel experimental studies. COMSOL Multiphysics® has been used to assess the impact of the various purposed arrangements of fibers within the mat. Drug release ...
J.G. Pieters, R. ElGamal, F. Ronsse
Faculty of Bioscience Engineering, Department of Biosystems Engineering, Ghent, Belgium
CFD simulations were carried out to predict the convective heat and mass transfer coefficients in the rice bed, and correlations were developed for the convective heat and mass transfer coefficients as a function of drying air flow rate. The developed correlations were used to extend the model developed by ElGamal et al. (2013) for thin-layer rice drying to volumetric heat and mass transfer in a ...
Comparing Isotropic and Anisotropic Brain Conductivity Modeling: Planning Optimal Depth-Electrode Placement in White Matter for Direct Stimulation Therapy in an Epileptic Circuit
L. C. Zaragoza, B. Hondorp, M. A. Rossi
ITESM, Monterrey, Mexico
Rush Medical College, Chicago, IL, USA
Rush University Medical Center, Chicago, IL, USA
The goal of our work was to calculate a patient-specific brain conductivity map for predicting the extent to which direct stimulation therapy can strategically propagate through pathological white matter. Our laboratory developed isotropic and anisotropic human brain finite element method (FEM) models derived from SPGR magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI), ...
A. Mulye, S. Potnis
Northeastern University, Boston, MA, USA
VIT, Mumbai, Maharashtra, India
We present an optimized and efficient design of an electrohydrodynamic (EHD) micropump for high performance in microscale and biological applications. We are targeting two major applications, a parylene C design for electrically-actuated medicine delivery, and a silicon-based pump design for on-chip cooling of microprocessors and SOCs. The EHD micropump works on the movement of microscale ...
G. Zhang, Y. Zhao, J. Hodge, J. Brcka, J. Faguet, E. Lee
Clemson University, Clemson, SC, USA
TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA
In using DEP for particle manipulation, researchers often use a formula to calculate the DEP forces in which the forces are proportional to the particle radius to the third power. This formula assumes that the electrical field, E, will not be affected by the presence of a particle, no matter what the actual size and the dielectric property of the particle are. This work confirms that the ...
L. T. Izu, Z. Coulibaly, B. Peercy
University of California-Davis, Davis, CA, USA
University of Maryland, Catonsville, MD, USA
This paper utilizes the COMSOL Multiphysics® general form PDE interface and MATLAB® to model stochastic calcium waves in a sarcomere (basic unit of a heart cell). The model we present here shows the evolution of waves generated from calcium being released stochastically from sites modeled as point sources. The release sites are distributed on z-disc (planes) in a hexagonal pattern, and their ...
Improving Detection Sensitivity for Nanoscale Targets Through Combined Photonic and Plasmonic Techniques
G. Zhang, Y. Zhao
Clemson University, Clemson, SC, USA
Photonic technique such as the whispering gallery mode (WGM) is often used for detection of small particles like bacteria and viruses. It offers good detection sensitivity and is advantageous over other detection techniques because the detection can be label free. However, the detection sensitivity may not be sufficient when the size of the detection target is in nanoscale. To change this, we use ...
Application of the Focused Impedance Method (FIM) to Determine the Volume of an Object within a Volume Conductor
M. A. Kadir, S. P. Ahmed, G. D. Al Quaderi, R. Rahman, K. Siddique-e Rabbani
Department of Biomedical Physics & Technology, University of Dhaka, Dhaka, Bangladesh
Department of Physics, Jahangirnagar University, Savar, Dhaka, Bangladesh
Department of Physics, University of Dhaka, Dhaka, Bangladesh
Focused Impedance Method (FIM), a new technique of electrical impedance measurement having high sensitivity in the central region, can sense the change in transfer impedance of an object embedded at a shallow depth within a volume conductor of unchanging background conductivity, using electrodes at the surface. This paper presents a new method for measuring the volume of such an embedded object ...
D. Mondal, C. RoyChaudhuri
Department of Electronics and Telecommunication Engineering, Bengal Engineering and Science University, Howrah, West Bengal, India
In this paper, the gross electrical characterization of biological cells on porous substrate is analyzed using COMSOL Multiphysics®. Dynamic electrical characterization during cell growth is used as a non-invasive and label-free technique to understand the growth kinetics of cells. It is observed from the COMSOL simulation that the percentage change in the current density is greater in porous ...
D. Iber, D. Menshykau, P. Germann, L. Lermuzeaux[2,3]
D-BSSE, ETH Zurich, Switzerland, SIB, Basel, Switzerland
D-BSSE, ETH Zurich, Basel, Switzerland
Department of Bioengineering, University of Nice-Sophia Antipolis, Nice, France
Morphogenesis is a tightly regulated process that has been studied for decades. Previously we developed data-based mechanistic models for a range of developmental processes with a view to integrate the available knowledge and to better understand the underlying regulatory logic. In our previous papers on simulating organogenesis in COMSOL Multiphysics® we discussed methods to efficiently solve ...