Technical Papers and Presentations

Ici vous trouverez les présentations issues des Conférences COMSOL à travers le monde. Réalisées par des utilisateurs de COMSOL Multiphysics, ces présentations explorent tous les domaines actuels d'innovation. Les applications couvrent pratiquement tous les secteurs industriels et impliquent des phénomènes électriques, mécaniques, fluidiques et chimiques. Utilisez la recherche rapide pour trouver les présentations les plus intéressantes dans votre domaine d'intérêt.

Estimating Cerebral Blood Flow using Electro-mechanical Modeling and Impedance Tomography Measurements

A. Jeremic, and T. Gadkari
McMaster University, Hamilton, ON, Canada

In this paper we propose a coupled electromechanical finite element model which combines the Navier-Stokes Equations of blood flow in an immersed boundary and the resulting deformed geometry with an electromagnetic model, which describes the electric field in the presence of deformation/structure changes caused by the blood flow in arteries.We derive least-squares estimates of the pressure drop ...

Some Clinical and Computational Studies On Haemodynamics In Stenosed Artery

A. Chanda, A.R. Choudhury, G. Ray, K. Dasgupta, and D. Nag
Jadavpur University, Kolkata, West Bengal, India

Atherosclerosis in arteries is caused by the formation of stenosis : fatty depositions, on the artery wall. In current medicine, the practice is to observe the maximum percentage occlusion at any arbitrary cross-section and diagnose the patient on that basis, which might not always present the real picture due to non-uniformity of the stenosis thickness. The present work attempts to simulate the ...

A Biological Gear in the Human Middle Ear

H. Cai, R.P. Jackson, C. Steele, and S. Puria
Stanford University, Stanford, CA, USA

To support high frequency transmission, the mammalian middle ear construction is unique. The middle ear bones are connected through two mobile joints, the malleus-incus joint (MIJ) and the incudostapedial joint (ISJ). These synovial joints, consisting of joint capsule and synovial fluid inside, play an important role in sound transmission. We developed our current FE model using COMSOL that ...

Large Scale Invasion Of New Species And Of Genetic Information

O. Richter, F. Suhling, and S. Moenickes
Technische Universität Braunschweig, Germany

The spatial dynamics of the invasion of new species and genetic dispersal is studied under the presumption of rising temperature by using a coherent approach of coupled partial differential equations of the reaction diffusion type. The nonlinear reaction terms model the population dynamics, genetic exchange and competition. Temperature reaction norms of reproduction rates are conferred by a two ...

Local Electroporation of Single Adherent Cells by Micro-Structured Needle Electrodes

K. K. Sriperumbudur[1], P. J. Koester[1], M. Stubbe[1], C. Tautorat[1], J. Held[2], W. Baumann[1], and J. Gimsa[1]
[1] University of Rostock, Chair of Biophysics, Gertrudenstr. 11a, 18057 Rostock, Germany
[2] Microsystem Material Laboratory, Department of Microsystems Engineering (IMTEK), University of Freiburg, Germany

In spite of its low throughput, Patch-Clamp is the established method for intracellular measurements of the transmembrane potential. To address this problem, we have developed new biosensor-chips with micro-structured needle electrodes (MNEs). MNE-penetration of single cells growing on the MNE-tips leads to a situation comparable to the whole-cell mode in classical Patch Clamp. MNE-penetration ...

Designing an Array of Nanocalorimeters for Screening Biochemical Interactions

F. Torres
Palo Alto Research Center

In this presentation we present our analysis of the PARC Nanocalorimeter. Calorimetry is basically the measuring of heat of chemical reactions or physical changes. Nanocalorimetry is Calorimetry at the Nanometer scale. The PARC Nanocalorimeter is a special type of Calorimeter, it consists of arrays of Nanocalorimeters. The PARC Nanocalorimeter is intended to be used for screening biochemical ...

Modelling Nutrient Transport in a Hollow-Fiber Membrane Bioreactor with Considerating the sub-Cellular Scale Mass Transfer

N. S. Abdullah1, D. B. Das2, and D. R. Jones1
1Department of Engineering Science, University of Oxford, Oxford, UK
2Department of Chemical Engineering, Loughborough University, Leicestershire, UK

Current bone tissue engineering protocols allow ex vivo growth of soft bone tissues in bioreactors. Recent experimental studies suggest that hollow fiber membrane bioreactors (HFMBs) may be used for growing 3-dimensional, clinically viable bone tissues. In order to facilitate the design of the HFMB for growing bone tissues, it is necessary to elucidate the quantitative relationships between cell ...

A Highly Effective Cellular Manipulation and Sorting Platform

A. Kose, B. Fischer, and H. Koser
Electrical Engineering Department, Yale University, New Haven, CT, USA

Ferrofluids are stable colloidal suspensions of nanosize magnetic particles in an organic or aqueous medium. Suspending nonmagnetic particles within a ferrofluid has led to numerous new areas of study. The simultaneous action of magnetic and hydrodynamic forces is responsible for the complex behavior of nonmagnetic particles within ferrofluids. As a result of nonzero fluid magnetization, a ...

A Mean Field Approach to Many-particles Effects in Dielectrophoresis

O. Nicotra, and A. La Magna
CNR-IMM Sezione di Catania, Catania, Italy

One of the major applications for dielectrophoresis is the selective trapping and fractionation in lab-on-a-chip devices. Nevertheless, many-particle effects due to high concentrations of biological material around electrodes can cause a rapid decrease of trapping efficiency in dielectrophoretic devices. In this contribution we present a new approach based on a drift-diffusion dynamics to study ...

Finite Element Analysis Approach for Optimization of Enzyme Activity for Enzymatic Bio-fuel Cell

Y. Song, and C. Wang
Florida International University, Miami, FL, USA

Enzymatic biofuel cells (EBFCs) are miniature, implantable power sources, which use enzymes as catalysts to perform redox reaction with biological fuels such as glucose. In this study using COMSOL Multiphysics, we use an EBFC chip, having three dimensional, highly dense micro-electrode arrays, fabricated by C-MEMS micro-fabrication techniques. Glucose oxidase (GOx) is immobilized on anodes for ...

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