Consultez les proceedings de la Conference COMSOL 2020
Understanding the Role of Nanomaterials in DNA Biosensors Through Finite Element Analysis
Tremendous progress is being made in the integration of nanoparticles into micro-analytical systems for biosensing. These materials are shown to enhance the analyte capture capability of biosensing platforms. We have implemented a computational model that considers the sensor’s geometry, ... En savoir plus
Comparing Isotropic and Anisotropic Brain Conductivity Modeling: Planning Optimal Depth-Electrode Placement in White Matter for Direct Stimulation Therapy in an Epileptic Circuit
The goal of our work was to calculate a patient-specific brain conductivity map for predicting the extent to which direct stimulation therapy can strategically propagate through pathological white matter. Our laboratory developed isotropic and anisotropic human brain finite element ... En savoir plus
Extending Engineering Simulations to Scientists: Food Safety and Quality Prediction Using COMSOL Multiphysics® and LiveLink™ for Excel®
The objective of this study was to develop an easy to use interface in Excel® that connects to not only the solvers in COMSOL Multiphysics®, but also existing databases of food properties, foodborne pathogenic microorganisms kinetics, and chemical kinetics, creating a comprehensive ... En savoir plus
Finite Element Analysis of Defibrillation Current Density in Pregnant Women
Although resuscitation during pregnancy is relatively uncommon and rarely causes death, they have a particularly large impact in terms of the mortality of the unborn child and long-term effects on families and society as whole. In this paper, we present a new 3D finite element model of a ... En savoir plus
Generation of Lofted NURBS Curves for 3D Model Generation with COMSOL Multiphysics®
A key challenge to finding quantitative solutions to biological problems is to model the complex 3D geometry of naturally occurring structures. Model generation often starts from serial sections from CT or MRI scans, confocal microscopy, or physical sectioning. In addition, prior to V4 ... En savoir plus
Development of a Multiphase, Multispecies Droplet Evaporation Model for Optimization of Desiccation Preservation Techniques
Biopreservation deals with the protection and storage of complex biologics such as proteins, lipids, and recently, mammalian cells. One preservation method, known as lyopreservation, involves placing a biologic inside a water droplet with some type of sugar excipient (sucrose, trehalose, ... En savoir plus
Singlet Oxygen Modeling for PDT Incorporating Local Vascular Oxygen Diffusion
Singlet oxygen (1O2) is the major cytotoxic agent that kills cells during photodynamic therapy (PDT). Based on a previously-developed model, the distance-dependent reacted 1O2 can be numerically calculated using finite-element method. We improved the model to include microscopic kinetic ... En savoir plus
Modeling Inertial Focusing in Straight and Curved Microfluidic Channels
Inertial focusing is a promising microfluidic technique for separating and concentrating cells of interest, processes routinely utilized in many medical procedures. This phenomenon is characterized by suspended particles in a flow spontaneously migrating across streamlines to equilibrium ... En savoir plus
Computational Modeling of the Electrohydrodynamics Influencing Trace Mercury Adsorption within Electric Utility Electrostatic Precipitators
Anthropogenic mercury (Hg) emissions increase the risk of neurological and neonatal health effects in humans through fish consumption. There are several technological approaches to controlling mercury emissions from coal combustion, including the injection of a powdered mercury sorbent ... En savoir plus
Coupled PDEs with Initial Solution from Data in COMSOL Multiphysics®
This paper presents information on techniques needed in COMSOL Multiphysics® to enable computational studies of coupled systems of PDEs for time-dependent non-linear problems. Furthermore, we demonstrate how to use data files as input for initial conditions. To illustrate the techniques, ... En savoir plus