A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry
Kristian Dreij, Qasim Ali Chaudhry, Bengt Jernström, Ralf Morgenstern, and Michael Hanke
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distribution of enzymes participating in the metabolism of foreign compounds i.e. bioactivation ...
INFN-LNL, Legnaro, Padova, Italy
The well known Pierce design of electron and ion diodes is the base of particle source extraction systems [1,2]. It was heavily studied up to 1960 with analog computing and it now offers us a known case against which to compare the precision of fluid and particle tracing codes. The ideal model assumes zero particle kinetic energy at cathode emission, which is well matched in many sources: the ...
Three-Dimensional Finite Element Modeling of Current Density in Maternal Transthoracic Defibrillation
A. Jeremic, J. Potts, E. Khosrowshahli
McMaster University, Hamilton, ON, Canada
McMaster University Hospital, Hamilton, ON, Canada
Although the cardiac arrest in pregnancy is a rare event it can have significant impact in terms of age of mother, mortality of unborn children and consequently long-term effect. One of the commonly used procedures in resuscitation is defibrillation. With recent advances in understanding pathophysiologies in pregnant women it became more obvious that previous studies should be extended to ...
Università degli Studi di Milano Bicocca, Milano, Italy
We present numerical models and field data that aid understanding of volcano-tectonic processes related to the propagation of inclined sheets and dykes under a stress field resulting from the inflation of a shallow magma chamber. Structural field data from the classical Cuillins cone-sheet complex (Isle of Skye) show that sheets have a constant average dip angle (45°), with pure dilational or ...
N.S. Lawand, J. van Driel, P.J. French
Electronic Instrumentation Laboratory (EILab), Faculty of Electrical Engineering, Mathematics and Computer Science (EEMCS), Delft University of Technology, Delft, The Netherlands
Delft University of Technology, Delft, The Netherlands
Cochlear Implants are implantable devices which bypasses the non-functional inner ear and directly stimulates the hearing nerve with electric currents thus enabling deaf people to experience sound again. Implant electrode array design is limited in electrode count, due to their large size in accordance to scala tympani (ST) with restrictions for deeper insertion in ST thus depriving access to ...
Reliability Enhancement of Bio MEMS based Cantilever Array Sensors for Antigen Detection System using Heterogeneous Modular Redundancy
L. S. Sundharam
Kumaraguru college of Technology, Coimbatore, Tamil nadu, India
The objective of the work is to propose a reliability enhancement model for antigen detection system (ADS) using bio MEMS based cantilever array sensors using heterogeneous modular redundancy technique. The reliability of the ADS is expressed in terms of the constituent sub systems which are heterogeneous not only in their respective structures and behaviors but also in their forms. The possible ...
Sz. Beleznai, I. Maros
Budapest University of Technology and Economics, Budapest, Hungary
General Electric Lighting, GE Hungary KFT, Budapest, Hungary
Two-dimensional plasma transport model was developed in COMSOL Multiphysics Plasma Module to investigate fundamental issues in ceramic metal halide (CMH) lamps starting using Ar/Hg penning gas mixture. The intent of this work is to provide insight into possible design rules that might be applied to the improvement of start-up in moderate pressure metal halide lamps. The model gives a complete ...
Electro Thermal Performance Prediction of Radio Frequency Ablation System for Efficient Cancer Treatment
C. Thiagarajan, V. Gnanasekar
ATOA Scientific Technologies Pvt Ltd, Whitefield, Bangalore, Karnataka, India.
Perfint Healthcare Pvt. Ltd, T.Nagar, Chennai, India.
Cancer causes significant human deaths. Radiofrequency ablation is an encouraging procedure for cancer treatment. The objective is to demonstrate the multiphysics simulation methodology. This paper summarizes the problem , governing equations, methodology, assumptions, simulation results and discussion related to the thermal performance prediction of radio frequency ablation on a homogeneous ...
K. Funamoto, I.K. Zervantonakis, R.D. Kamm
Tohoku University, Sendai City, Miyagi, Japan
Massachusetts Institute of Technology
Numerical simulation of oxygen tension was performed to develop a microfluidic device for three-dimensional real-time observation of cellular response under hypoxia. The optimal experimental condition was obtained through investigations of effects of parameters, such as device thickness and flow rates of media and gas, on oxygen tension.
T. Satyanarayana, V. Sai Pavan Rajesh
NPMASS Centre, Lakireddy Bali Reddy Autonomous Engineering College, Mylavaram, Andhra Pradesh, India
Lakireddy Bali Reddy Autonomous Engineering College, Mylavaram, Andhra Pradesh, India
The most commonly used type of resonator is the AT-cut, where the quartz blank is in the form of a thin plate cut at an angle to the optic axis of the crystal. This paper reports the modeling of a quartz oscillator for a resonant frequency analysis based on piezoelectric effects. The proposed oscillator consists of a single quartz disc with two electrodes on the top and bottom surfaces of the ...