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Axon propagation model

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Hi there,

I'm trying to create a nerve conduction model and am running into some trouble. The basic idea is to model axon nodes of ranvier as spheres with current density that is modulated to mimic the current waveform in an axon as an action potential travels through it. I started off with one sphere, created an array of it to approximate the axon, and applied an appropriate current waveform using the interpolation function.

This waveform currently affects each sphere in the array at the exact same time, but I would like it to start at the far left sphere and jump from sphere to sphere (mimicking saltatory conduction) all the way to the rightmost sphere. I tried to fix this by using a piecewise function and editing the start and end times using a space-dependent equation, but I keep getting a 'variable not found' error when I try to reference distance along the x axis. I could edit each sphere's current function individually but with 400 spheres, this would be impractical. Any advice on how to proceed would be greatly appreciated.


0 Replies Last Post 3 nov. 2021, 15:41 UTC−4
COMSOL Moderator

Hello Jonah Mudge

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