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Découvrez comment la simulation multiphysique contribue à faire progresser la recherche dans le monde entier grâce à des applications innovantes

La modélisation et la simulation multiphysiques stimulent l'innovation dans l'industrie et le monde universitaire, comme en témoignent les nombreuses applications présentées chaque année par des ingénieurs, des chercheurs et des scientifiques dans leurs articles techniques et posters lors des conférences COMSOL.

Inspirez-vous des travaux présentés lors des dernières conférences, rassemblés ci-dessous. Pour trouver une présentation en particulier ou affiner votre recherche par domaine d'application, année ou lieu de conférence, utilisez l'outil de recherche rapide.

Consultez les proceedings de la Conference COMSOL 2026

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Bioscience and Bioengineering

Optimizing Elastomeric Mechanical Cell Stretching Device

A-J. Mäki [1], J. Kreutzer [1], P. Kallio [1],
[1] BioMediTech Institute and Faculty of Biomedical Sciences and Engineering, Tampere University of Technology, Tampere, Finland

Cell morphology, orientation, and fate of differentiated stem cells can be affected by mechanical stimulation. Mechanobiological studies help to understand the molecular mechanisms of cells sensing and responding to mechanical cues. Previously, we have developed a vacuum-operated ... En savoir plus

Characterization of Biochemical and Physical Parameters of a Skin Equivalent in a Two-Organ-Chip

H-H. Hsu [1], K. Schimek [2], G. Lindnder [3], J. Jan Kornet [1], Moritz Boehme [1], Uwe Marx [3], Ralf Pörtner [1],
[1] Institute of Bioprocess- and Biosystems Engineering, Hamburg, Germany
[2] Department of Biotechnology, Berlin, Germany and TissUse GmbH, Berlin, Germany
[3] TissUse GmbH, Berlin, Germany

Background and novelty Organ-on-a-chip-systems represent a powerful alternative to substance testing in animal trials. The basic idea behind this approach is to emulate the smallest physiological unit of an organ on a chip. For this purpose, micro-environments must be created, that ... En savoir plus

Bioheat Dissipation of a Implantable Brain-Machine Interface

J. M. Herrera Morales [1],
[1] Wyss Center for Bio and Neuroengineering, Switzerland

Brain-Machine Interfaces (BMI) provide a direct communication link between brain and external devices such as speech synthesizers and robotic prosthesis to restore speech and movement in persons affected by Spinal Cord Injuries or neurodegenerative diseases such as Amyotrophic Lateral ... En savoir plus

3D Optical Human Eye Model Based on COMSOL Multiphysics® to Provide a Test Bench for Laser Surgery

S. Regal [1], R. Delattre [1], M. Ramuz [1],
[1] Department of Flexible Electronics, Ecole Nationale Supérieure des Mines, Centre Microélectronique de Provence CMP-EMSE, MOC, Gardanne, France

We present here the development of an optical human eye model – based on Ray Optics module in order to reproduce the eye optical properties. Current simulations in literature do not fully cover the light propagation inside all parts of the eye by taking into account the absorption but ... En savoir plus

Simulating 200 kHz AC Tumor-Killing Fields with COMSOL Multiphysics®

K. W. Carlson [1], N. Paudel [2], S. Dokos [3], J. A. Tuszynski [4],
[1] Beth Israel Deaconess Medical Center - Harvard Medical School, Boston, MA, USA
[2] IEEE, Greenville, NC, USA
[3] University of New South Wales, Sydney, NSW, Australia
[4] University of Alberta, Edmonton, AB, Canada

Alternating 200 kHz electric fields ~2 V/cm (Tumor Treating Fields, ‘TTFields’) kill cancer cells by disrupting the delicate orchestration of chromosome spindle formation, but the exact mechanism of action is unknown. The likely suspects are polarized intracellular molecules such as ... En savoir plus

Multi-objective Optimization of Microneedle Design for Transdermal Drug Delivery

M. Sarmadi [1], K. McHugh [1], R. Langer [1], A. Jaklenec [1],
[1] David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA

Microneedles have been recognized as a potent and novel method of transdermal drug delivery over the last decade. Despite recent advances in nano- and microfabrication techniques, less is known about the structural properties and design optimization of microneedles in a systematic ... En savoir plus

Development of Electrochemical Methods for Differentiation of the Catecholamine Neurotransmitters

I. Fritsch [1], M. Abrego Tello [1],
[1] University of Arkansas, Fayetteville, AR, USA

Neurological disorders afflict tens of millions in the US. We are developing technology to advance capabilities for monitoring the neurotransmitters, dopamine, norepinephrine, and epinephrine (the catecholamines), to facilitate direct observations of their mutual interactions in brain ... En savoir plus

Computational Modeling of Diffusion-Based Transport from Differing Designs of Drug-Containing Sutures

S. Jorgensen [1], J. R. Sanders [1], Y. W. Liu [1],
[1] Tennessee Technological University, Cookeville, TN, USA

Dermal wounds have a high occurrence, and wounds that require surgical closure have been shown to result in up to 11 million keloid scars that might result from abnormal healing of these wounds. While small and superficial wounds generally heal effectively without treatment, large, deep, ... En savoir plus

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