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Ici vous trouverez les présentations issues des Conférences COMSOL à travers le monde. Réalisées par des utilisateurs de COMSOL Multiphysics, ces présentations explorent tous les domaines actuels d'innovation. Les applications couvrent pratiquement tous les secteurs industriels et impliquent des phénomènes électriques, mécaniques, fluidiques et chimiques. Utilisez la recherche rapide pour trouver les présentations les plus intéressantes dans votre domaine d'intérêt.

Consultez les proceedings de la Conference COMSOL 2024

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Boston 2024

Munich 2023

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Bioscience and Bioengineering

Microstimulation in The Brain: Does Microdialysis Inuence the Activated Volume of Tissue?

D. Krapohl[1][3], S. Loeffler[2], A. Moser[2], and U.G.Hofmann[1]

[1]Institute for Signalprocessing, University of Luebeck, Lübeck, Germany
[2]Institute for Neurology, University of Luebeck, Lübeck, Germany
[3]Department of Information Technology and Media, Mid Sweden University, Sundsvall, Sweden

Deep Brain Stimulation (DBS) has been established as an effective treatment for Parkinson's disease and other movement disorders. The stimulation is currently administered using tetrode-macroelectrodes that target the Subthalamic Nucleus (STN). This often leads to side effects which bias ... En savoir plus

Modeling Interface Response in Cellular Adhesion

G. Megali[1], D. Pellicanò[1], M. Cacciola[1], F. Calarco[1], D. De Carlo[1], F. Laganà[1], and F.C. Morabito[1]

[1]DIMET Department, Faculty of Engineering, University “Mediterranea” of Reggio Calabria, Reggio Calabria, Italy

Constitutive properties of living cells are able to withstand physiological environment as well as mechanical stimuli occurring within and outside the body. We examined fluid flow and Neo-Hookean deformation related to the rolling effect. A mechanical model to describe the cellular ... En savoir plus

Design and Simulation of a Microscale Magnetophoretic Device for the Separation of Nucleated Fetal Red Blood Cells from Maternal Blood

G. Schiavone[1], D.M. Kavanagh[2], and M.P.Y Desmulliez[2]

[1]Politecnico di Torino, Torino, Italy
[2]MIcroSystems Engineering Centre, School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh, Scotland, United Kingdom

Intense research has been carried out into methods that aim at harvesting fetal cells from maternal blood as substitutes to amniocentesis and chorionic villus sampling. This work focuses on the separation of fetal nucleated red blood cells from the maternal circulation based on their ... En savoir plus

Modeling the Behavior of Phased Arrays in Brain Tissue: Application to Deep Brain Stimulation

V. Valente[1], A. Demosthenous[1], and R. Bayford[2]

[1]Department of Electronic & Electrical Engineering, University College London, London, United Kingdom
[2]Department of Natural Sciences, Middlesex University, London, United Kingdom

Deep Brain Stimulation (DBS) is a therapeutic tool used for a number of neurological disorders including chronic pain, incontinence and movement disorders, such as Parkinson’s disease. DBS consists of the low-frequency stimulation of an area of the brain, known as basal ganglia. ... En savoir plus

Impedance Spectroscopy and Cell Constant of the Electrodes for Deep Brain Stimulation

E. Vinter[1], S. Petersen[1], J. Gimsa[2], and U. van Rienen[1]

[1]Institute of General Electrical Engineering, University of Rostock, Rostock, Germany
[2]Institute of Biology, University of Rostock, Rostock, Germany

To achieve a deeper understanding of the mechanism of the Deep Brain Stimulation (DBS) scientists use more and more numerical simulations. DBS inhibits overreaching brain activity via electric pulses that send into the brain by electrodes. Different electrode parameters such as geometry, ... En savoir plus

Thin Membrane Modelling for the Electrical Stimulation of Auditory Nerve

A. Grünbaum[1], S. Petersen[1], H.W. Pau[2], and U. van Rienen[1]

[1]IEF funded by DFG Research Training Group 1505/1 Welisa, University of Rostock, Rostock, Germany
[2]Otolaryngology “Otto Körner”, University of Rostock, Rostock, Germany

Modeling of 2-5 μm thin membranes into a cochlea with a width of 2 cm is computationally. The paper is focused on two approximative methods used to overcome this problem and in addition a simple model challenging of a plate capacitor with a thin membrane of different thickness in ... En savoir plus

3D-Simulation of Action Potential Propagation in a Squid Giant Axon

R. Appali[1], S. Petersen[1], J. Gimsa[2], and U. Rienen[1]
[1] Institute of General Electrical Engineering, Chair of Electromagnetic Field Theory, University of Rostock, Germany
[2] Institute of Biology, Chair of Biophysics, University of Rostock, Germany

Study of neurons plays a key role in the fields of basic and medical research aiming at the development of electrically active implants. The Fitzhugh-Nagumo equations are used to model and simulate the spike generation and propagation in a squid giant axon using COMSOL Multiphysics® 3.5a ... En savoir plus

Local Electroporation of Single Adherent Cells by Micro-Structured Needle Electrodes

K. K. Sriperumbudur[1], P. J. Koester[1], M. Stubbe[1], C. Tautorat[1], J. Held[2], W. Baumann[1], and J. Gimsa[1]
[1] University of Rostock, Chair of Biophysics, Gertrudenstr. 11a, 18057 Rostock, Germany
[2] Microsystem Material Laboratory, Department of Microsystems Engineering (IMTEK), University of Freiburg, Germany

In spite of its low throughput, Patch-Clamp is the established method for intracellular measurements of the transmembrane potential. To address this problem, we have developed new biosensor-chips with micro-structured needle electrodes (MNEs). MNE-penetration of single cells growing on ... En savoir plus

Optimal PDE Control Using COMSOL Multiphysics

I. Neitzel[1], U. Prüfert[2], and T. Slawig[3]

[1]Technische Universität Berlin / SPP 1253
[2]Technische Universität Berlin / Matheon
[3]Excellence Cluster The Future Ocean, Algorithmic Optimal Control - Oceanic CO2-Uptake/SPP 1253

An optimal control problem (OCP) is studied to a PDE of elliptic type as well as state constraints. The resulting optimality system contains two PDEs, one algebraic equation and the so called complementary slackness conditions, i.e. dual products between function spaces. At this point, ... En savoir plus

Coupled Electromagnetics-Multiphase Porous Media Model for Microwave Combination Heating

V. Rakesh, and A. Datta
Dept. of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA

Although microwave heating has been studied in great detail, microwave combination heating has not. This work investigated this in a novel microwave combination system that heats the sample through a combination of microwaves and hot air. The study used a coupled electromagnetics ... En savoir plus

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