Harvey Buck, Roche Diagnostics Operations, Inc., Indianapolis, IN, USA
The test strips in glucose monitors, widely used by people with diabetes to maintain good health, are sensitive to chemical interferences and environmental conditions. The manufacturing process and electrode configuration of these strips also affects response accuracy. Researchers at Roche Diagnostics Operations, Inc. used multiphysics simulation to analyze the chemical reactions and voltage response in their glucometers.
Using COMSOL Multiphysics, Harvey Buck, principal scientist at Roche, investigated different configurations and materials used in the test strips. He analyzed the electrical response to an applied voltage during the chemical reaction catalyzed in a sample. Through numerical simulation, he predicted the sensitivity of electrical impedance measurements to mechanical properties of the sensor. He also optimized the electrode configuration, maximized sensitivity to cell fraction in a sample, and minimized sensitivity to manufacturing tolerances. These simulation results have given the Roche team a better understanding of their integrated sensor design for glucose monitoring.
Suggested Stories
Battling Corrosion in Nuclear Waste Storage Facilities
Nuclear sites in Italy are being decommissioned, leaving questions about how to safely manage and store radioactive ...
Lighting the Way for Improved Synchrotron Vacuum Chambers at RadiaSoft
One of the goals of the Argonne National Laboratory (ANL) is to increase the brightness of synchrotron beams for the ...
Efficient Grid Operation and Maintenance with Simulation Apps
Engineers at NARI Group Corporation developed the Cable Condition Analysis Expert System App, based on their ...
Investigating Vibroacoustic Properties in Moth Wings for Acoustic Camouflage
Researchers at the University of Bristol modeled the acoustic camouflaging properties of moth wing scales to gain a ...
