Harvey Buck, Roche Diagnostics Operations, Inc., Indianapolis, IN, USA
The test strips in glucose monitors, widely used by people with diabetes to maintain good health, are sensitive to chemical interferences and environmental conditions. The manufacturing process and electrode configuration of these strips also affects response accuracy. Researchers at Roche Diagnostics Operations, Inc. used multiphysics simulation to analyze the chemical reactions and voltage response in their glucometers.
Using COMSOL Multiphysics, Harvey Buck, principal scientist at Roche, investigated different configurations and materials used in the test strips. He analyzed the electrical response to an applied voltage during the chemical reaction catalyzed in a sample. Through numerical simulation, he predicted the sensitivity of electrical impedance measurements to mechanical properties of the sensor. He also optimized the electrode configuration, maximized sensitivity to cell fraction in a sample, and minimized sensitivity to manufacturing tolerances. These simulation results have given the Roche team a better understanding of their integrated sensor design for glucose monitoring.
Suggested Stories
Greening the Heart of the City: An Urban Rooftop Drainage System Inside a Garden Fence
TL-Engineering, a simulation consultant, teamed up with a professor, civil engineer, and sound barrier company to ...
Manipulate and Control Sound: How Mathematical Modeling Supports Cutting-Edge Acoustic Metamaterials Research
Researchers at Duke University are using numerical modeling to develop metamaterial structures for acoustic cloaking. ...
Floating on Sound Waves with Acoustic Levitation
As part of an industry that saves lives on a regular basis, pharmaceutical companies are in need of systems that can ...
Virtually Optimizing Metasurface Topology with a Genetic Algorithm
To optimize a metasurface topology for an optical antenna design, an engineer from the Air Force Institute of ...
