Technical Papers and Presentations

Ici vous trouverez les présentations issues des Conférences COMSOL à travers le monde. Réalisées par des utilisateurs de COMSOL Multiphysics, ces présentations explorent tous les domaines actuels d'innovation. Les applications couvrent pratiquement tous les secteurs industriels et impliquent des phénomènes électriques, mécaniques, fluidiques et chimiques. Utilisez la recherche rapide pour trouver les présentations les plus intéressantes dans votre domaine d'intérêt.

Dynamic Simulation Of Particle Self-Assembly Applied To Microarray Technology

V. Di Virgilio, A. Coll, S. Bermejo, and L. Castañer
Universitat Politecnica de Catalunya, Barcelona, Spain

In this work we want to explore some techniques, microfluidic and electrospray-ionization based, suitable for dynamic microarrays\' fabrication. The fabrication techniques are based on manipulation and self-assembly of selective coated micro and nanobeads. The simulation will include electro-osmotic flow, species transport, and electrostatics.

Modeling of Retinal Electrical Stimulation Using a Micro Electrode Array Coupled with the Gouy-Chapman Electrical Double Layer Model to Investigate Stimulation Efficiency

F. Dupont, R. Scapolan, C. Condemine, J.F. Bêche, M. Belleville, and P. Pham
CEA, LETI, Minatec, Grenoble, France

The electrical stimulation for retinal implant has known significant improvements in the last decades with many implantations and experimentations. The ability to create better controlled and adapted signals to increase the efficiency in stimulation is a major objective. The aim of this study is to develop a numerical platform based on COMSOL Multiphysics to simulate different waveforms. The ...

Computer Simulation Of Haematopoietic Stem Cells Migration Using COMSOL Multiphysics

G. Bencheva
Institute for information and communication technologies, Bulgarian Academy of Sciences, Sofia, Bulgaria

Various haematological diseases, including leukaemia, are characterized by abnormal production of particular blood cells. Two important properties of haematopoietic stem cells (HSCs) are used in their therapy, namely: a) rapid migratory activity and ability to \'\'home\'\' to their niche in the bone marrow; b) high self-renewal and differentiation capacity, responsible for the production and ...

An Elastic and Hyperelastic Material Model of Joint Cartilage - Calculation of the Pressure Dependent Material Stress in Joint Cartilage

T. Reuter, and M. Hoffmann
fzmb GmbH
Research Centre of Medical Technology and Biotechnology
Bad Langensalza, Germany

In this paper we introduce a elastic and hyperelastic model to describe the pressure dependent material stress in joint cartilage. We used the pressure dependent E-modulus E = f(s) to calculate the material stress. E = f(s) is a degree 4 polynomial . The indentor was pressed 0.4 mm into the tissue. The results show that the maximal stress at the contact zone between indentor and cartilage account ...

3-Dimensional Blood Cooling Model inside a Carotid Bifurcation

R. Sikorski[1], T. Merrill[1]
[1]Rowan University, Glassboro, NJ, USA

Stroke is caused by an interruption of brain blood supply and is one of the leading causes of death and disability. A mild reduction of 2-5°C in tissue temperature through hypothermia has shown reduced tissue infarct size, increased tissue recovery, and positive neurological effects. This paper seeks to predict the outlet blood temperature in the common carotid bifurcation branches. In our ...

Microwave Exposure System for In Vitro and In Vivo Studies

C. Nadovich[1, 2], W. D. Jemison[2], J. A. Stoute[3], C. Spadafora[4]
[1]Lafayette College, Easton, PA, USA
[2]Clarkson University, Potsdam, NY, USA
[3]Pennsylvania State University, Hershey, PA, USA
[4]INDICASAT AIP, Ciudad del Saber, Panama

A computer controlled microwave exposure system and specialized applicators were constructed for the purpose of facilitating accurate observations of microwave radiation effects on uninfected and infected biological tissue in vitro and in vivo under different electromagnetic modalities and exposure configuration. To address diverse requirements, three different applicators were developed: a ...

On the Influence of Cancellous Bone Structure upon the Electric Field Distribution of Electrostimulative Implants

U. Zimmermann[1], R.Bader[2], U. van Rienen[1]
[1]Institute of General Electrical Engineering, University of Rostock, Rostock, Germany
[2]Department of Orthopaedics, University Medicine Rostock, Rostock, Germany

Since the 1980s, the accelerating effect of electromagnetic fields on bone regeneration is used to treat complicated fractures and bone diseases. At the University of Rostock, an electrostimulative hip revision system is developed, basing on the method of Kraus-Lechner. This method requires an electric fields between 5 and 70 V/m. The bone used for the simulations consisted of two homogenous ...

Microstimulation in The Brain: Does Microdialysis Inuence the Activated Volume of Tissue?

D. Krapohl[1][3], S. Loeffler[2], A. Moser[2], and U.G.Hofmann[1]

[1]Institute for Signalprocessing, University of Luebeck, Lübeck, Germany
[2]Institute for Neurology, University of Luebeck, Lübeck, Germany
[3]Department of Information Technology and Media, Mid Sweden University, Sundsvall, Sweden

Deep Brain Stimulation (DBS) has been established as an effective treatment for Parkinson's disease and other movement disorders. The stimulation is currently administered using tetrode-macroelectrodes that target the Subthalamic Nucleus (STN). This often leads to side effects which bias the surrounding areas, e.g. the speech centre. Targeting a specific brain region can better be achieved with ...

Implementation of Cable Theory of Neurophysiology in COMSOL

G. V. Narayanan
University of Toledo, Toledo, OH, USA

Computational neuroscience seeks to develop mathematical models describing how the nervous system or some part of it carries out certain operations. Unfortunately, realistic models are typically so complex as to preclude a detailed mathematical analysis. Hence, a simplified 1-D cable theory has been developed, and this theory is used in neuroscience to study the behavior of neurons.In this paper, ...

Cavity Sprayer Flow Optimization for Medical Devices Industry

T. Selvam, V.P. Kotte, and M. Marimuthu

HCL Technologies Ltd, Chennai, Tamil Nadu, India

Globally in Otolaryngology industry, Sinusitis is one of the most common diseases related to the nose. Sinusitis is caused when the cilia fail to move the mucus. As a result sinus tissue gets infected that leads to blockage of the sinuses. All the sinusitis can not be cured through drugs and certain require surgery. When a sinus cavity subjected to a nasal endoscopic surgical procedure, one of ...

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