Effects of Flow and Diffusion on Blood Coagulation in Platelet Poor Plasma: a Two-way Coupling Between Hemodynamics and Biochemistry
D. Magnabosco[1,2], H. van Ooijen, B. Bakker, R. van den Ham
Politecnico di Milano, Milan, Italy
Philips Research, Eindhoven, The Netherlands
Enzyme reactions, blood flow and diffusion in human vasculature play interacting and fundamental roles in blood coagulation. In this complex mechanism, the balance between blood and clot is a delicate equilibrium, whose tight regulation is vital to avoid pathologies such as bleeding and thrombosis. The secondary hemostasis triggered by tissue factor in platelet poor plasma is studied up to ...
M. Weber, M. Reed
Yale University, New Haven, CT, USA
Arrays of vertical pillars, Micro Purification Chips, have been widely used for analyte capture from liquid samples [Henderson et. al, 2006], [Toner et. al, 2007], [Stern et. al, 2010]. However exact understanding of the capture efficiency mechanisms has not been previously explained. Here we present a model in COMSOL Multiphysics® which calculates analyte capture efficiency based on initial ...
J. Schillings , O. Doche , J. Deseure ,
 LEPMI, Grenoble, France
 SIMAP, Grenoble, France
The dependency of electrochemical processes performances on mass transfer is well-known. Electrolyte flow in the vicinity of electrodes surface can enhance reactions due to increased mass transfer. This flow can be generated by the production of a gaseous phase, leading to a natural bubble-driven convection flow. As a drawback, gas bubbles also modify electrodes active surface and the ...
Numerical Modeling of the Original and Advanced TEMKIN Reactor for Catalysis Experiments in Laboratory Scale - new
D. Götz, M. Kuhn, P. Claus
Ernst-Berl-Institute/Chemical Technology II, Darmstadt, Germany
Many industrial, especially heterogeneously catalysed, processes are characterised by a strong interaction between the reaction kinetics and transport phenomena. Because experiments in laboratory scale can be very time- and cost-intensive, Temkin andKul’kova developed a new reactor design for the direct testing of industrial catalysts. Based on this concept of linearly alternating catalyst and ...
M. Hackert-Oschätzchen, M. Penzel, P. Plänitz, A. Schubert
Chemnitz University of Technology, Chemnitz, Germany
GWT-TUD, Dresden, Germany
Fraunhofer Institute for Machine Tools and Forming Technology IWU, Chemnitz, Germany
Gallium nitride (GaN) and its related nitride alloys with special physical properties are in technical areas of high interest. The growing of gallium nitride boules on non-native sapphire or silicon carbide requires complicated mechanisms of defect reduction in the lattice structure. Thus the production of gallium nitride substrates is a challenge. Hydride Vapor Phase Epitaxy (HVPE) is a ...
K.O. Lund, C.M. Lord
Kurt Lund Consulting, Del Mar, CA, USA
Lord Engineering Corp., Encinitas, CA, USA
Pressure-drop experiments were conducted for the turbulent, compressible flow of air in a small, slender tube, and modeled with COMSOL heat transfer module, and analytically. A scalar integration variable is introduced which integrates the mass velocity [kg/m²s] over the inlet area and iteratively equates this to the input mass flow [kg/s]. For computation, the temperature specification is ...
J. Ebert, S. Ghosal, A. Emami-Naeini
SC Solutions, Sunnyvale, CA, USA
This paper describes the development of a COMSOL model of Electro-Chemical-Mechanical Planarization (ECMP) that was validated with experimental data. ECMP is used for processing of semiconductor wafers. We developed a 2D model of flow of phosphoric acid solution (the electrolyte) between two parallel plates that focuses on the physics and electrochemistry in ECMP. The model includes steady-state ...
C. Gomez , R. F. Coker , J. Knox , G. Schunk 
 NASA MSFC, Huntsville, AL, USA
The primary interest of the VC (Vacuum Characterization) test is to experimentally characterize the adsorption and vacuum desorption of CO2 and water vapor of a pelletized sorbent bed in a large diameter column. The VC test article is shown in Figures 1 and 2. The aluminum canister is 3” in diameter and approximately 8” long allowing for variable sorbent bed loads from 1” to 6” in length. A ...
F. J. Navarro-Brull , P. Poveda , J. Ramis , R. Gómez ,
 Departament de Química Física, Universidad de Alicante, Alicante, Spain
 Departament de Física, Enginyeria de Sistemes i Teoria del Senyal, Universidad de Alicante, Alicante, Spain
Possible drawbacks of microreactors are inefficient reactant mixing due to the predominance of laminar flow and clogging (when solid-forming reactions are performed or solid catalyst suspensions are used). Ultrasound has been successfully implemented not only to prevent these problems but also for its well-known mixing and particle-dispersion effects. Several configurations have been used for ...
Simeon Cavadias , Cédric Guyon , Gerrardo Vera De la Cruz ,
 Institut Pierre-Gilles de Gennes (IPGG) - UPMC, France
 Chimie-ParisTech - Institut Pierre-Gilles de Gennes (IPGG) , France
 Master Nuclear Energy, ISTN (Saclay), France
Emulsions, small liquid droplets of oil in water or water in oil, find wide application in, pharmaceutical products, fine chemicals, analytical chemistry. Microfluidic devices allow creation of uniform droplets with a tight distribution. The COMSOL Multiphysics® software model presented here is an extension of the tutorial “Droplet Breakup in a T- junction”. In this tutorial uniform droplets ...