Fibre-Optic Microsensor Based on Surface Plasmon Resonance in a Microfluidic Cell : An Experimental and Numerical Multiphysics Approach
G. Louarn, T. Makiabadi, V. Le Nader, and M. Kanso
Institut des Matériaux Jean-Rouxel (IMN), CNRS- Université de Nantes, France
In the last decade, the surface plasmon resonance (SPR) has become a very sensitive technique for real-time detection in many application areas. Considering the fiber optic concept and the important needs for analyzing biomolecular reactions through automated and miniaturized components, fiber optic sensors based on the SPR technique are becoming an important choice in the field of sensing. In ...
E. Giuri, A. Ricci, and S.L. Marasso
Politecnico di Torino, Materials Science and Chemical Engineering Department, Turin, Italy
In this work, time dependent thermal analyses, performed on the 3D FE model of a multilevel Lab on Chip (LOC) platform are executed in order to gain insight into the temperature distribution within the device. By means of the COMSOL Multiphysics CAD import module, an extremely close 3D reproduction of the actual device, allowing to probe temperatures in those regions where an experimental ...
S. Druart, D. Flandre, and L.A. Francis
Université catholique de Louvain - ICTEAM, Louvain-la-Neuve, Belgium
In this paper, a methodology to simulate the electric behavior of spiral inductances is presented and discussed. All the methodology is built with the COMSOL software used with the Matlab scripting interface and then allows performing fully parameterized simulations. The program architecture is explained and is used to simulate two applications. The first calculates the voltage induced by an ...
Impact of Velocity and Interfacial Tension on the Performance of Horizontal Wells in Gas Condensate Reservoirs
P. Ghahri, M. Jamiolahmady, and M. Sohrabi
Heriot Watt University, Edinburgh, United Kingdom
Drilling horizontal wells (HWs) has recently received renewed attentions with the increasing trend in exploitation of tight gas reservoirs. An accurate estimation of productivity of such systems using a numerical simulator is a challenging task, because its 3D simulation requires a fine grid exercise to capture the abrupt variation of fluid and flow parameters around the wellbore. This is ...
P. Lezuo, M. Stoddart, and M. Alini
AO Research Institute, Davos, Grison, Switzerland
We aim to develop an in vitro culture system to mimic the human bone marrow stem cell niche in an artificial perfusion bioreactor environment to culture human adult stem cells. State of the art human bone marrow stem cell research shows that even smallest changes in the physical, thermo dynamical or biochemical environment induce a differentiation of human bone marrow stem cells into other cell ...
E. Zinterl, and G. Jakopic
JOANNEUM RESEARCH Forschungsgesellschaft mbH,
MATERIALS-Institute for Surface Technologies and Photonics
Heating or cooling of stored fluids by thermal energy exchange with the enclosing walls may be enhanced by improving the efficiency of energy transfer; energy loss to the ambient is equalized for all simulations. Buoyancy driven internal natural convective flow is assumed to be the main energy transfer mechanism. In Newtonian fluids dynamic behaviour is described by the Navier-Stokes ...
The Effect of the Disintegration of Chemical Stratification on the Time-dependent Behavior of the Earth’s Mantle
A. Galsa, and M. Herein
Based on recent results from seismology, geochemistry etc. the distinct chemical character of the D’’ layer (lowest part of the mantle around the Earth’s core) has appeared unequivocally. Numerical calculations have been carried out to investigate the effect of the disintegration, mixing and homogenization of the dense D’’ on the time-dependent behavior of mantle convection. A ...
Research & Technology
Rick has a BS in Physics, a ScM in Geological Sciences, and a PhD in Physics. He worked at Air Force Geophysics Laboratory, Conoco Petroleum Exploration Research, and, since 1989, has been at the DuPont Experimental Station. In this industrial setting, Rick has had opportunity to work on a great diversity of problems ranging from traditional engineering studies, using commercial finite-element ...
University of Miami
Electric fields are present in biological systems at multiple spatial and temporal scales. Electroosmotic flow results from the action of electric field on the electrical double layer, formed at the fluid/solid or fluid/membrane interface and characterized by its zeta-potential. For the physiological value of zeta-potential (50 mV) and a single charged protein of average size, electroosmotic ...
A Method for Efficient Calculation of Diffusion and Reactions of Lipophilic Compounds in Complex Cell Geometry
Kristian Dreij, Qasim Ali Chaudhry, Bengt Jernström, Ralf Morgenstern, and Michael Hanke
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
A general description of effects of toxic compounds in mammalian cells is facing several problems. Firstly, most toxic compounds are hydrophobic and partition phenomena strongly influence their behaviour. Secondly, cells display considerable heterogeneity regarding the presence, activity and distribution of enzymes participating in the metabolism of foreign compounds i.e. bioactivation ...