R. Penjweini, M. M. Kim, T. C. Zhu
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
Introduction: Singlet oxygen (¹O₂) has a critical role in the cell-killing mechanism of photodynamic therapy (PDT). Therefore, in this study, the distance-dependent reacted ¹O₂ is numerically calculated using finite-element method (FEM). Herein, we use a model [Ref. 1] that has been previously developed to incorporate the diffusion equation for the light transport in tissue and the ...
KTH Royal Institute of Technology, Stockholm, Sweden
Corrugated board is produced on a machine where the corrugated medium is glued between two flat paper surfaces, the liners. The board is cut into sheets and stored in a stack until suitable moisture content has been reached. The sheets are then cut and creased into blanks for the production of boxes and other products. If the moisture content is too high, there is a risk for cutting problems in ...
P. D. Hanasi, B. G. Sheeparamatti, B. B. Kirankumar
Basaveshwar Engineering College, Bagalkot, Karnataka, India
Micro cantilevers are the basic MEMS structures, which can be used both as sensors and actuators. The . The objective of this work is to study concept of pull-in voltage and how to reduce the same. Voltage is applied to upper cantilever beam and lower contact electrode is made as ground. By increasing common area between cantilever beam and contact electrode, and also by reducing thickness of the ...
A. V. Lakshmi, K. C. Devi
PSG College of Technology, Coimbatore, Tamil Nadu, India
This paper presents the design and simulation of a thermal sensor using COMSOL Multiphysics® software for the detection of low body temperature syndrome which can allow the early detection of cancer. This sensor is made of an alloy consisting of two materials with different coefficients of thermal expansion. The main objective of this work is to investigate the structural change in the sensor ...
U. Shukla, and D. Gupta
 Department of Materials and Metallurgical Engineering, Indian Institute of Technology Kanpur, Uttar Pradesh, India
One of the major challenges faced by the semiconductor industry is that electronic circuits produce a lot of heat energy during their operation. And with the current scenario where the gates are packed so much close together, then the problem of heat generation has become extremely significant. So we are working towards the efficient heat management and dissipation solution for the heat generated ...
K. K. Sriperumbudur, P. J. Koester, M. Stubbe, C. Tautorat, J. Held, W. Baumann, and J. Gimsa
 University of Rostock, Chair of Biophysics, Gertrudenstr. 11a, 18057 Rostock, Germany
 Microsystem Material Laboratory, Department of Microsystems Engineering (IMTEK), University of Freiburg, Germany
In spite of its low throughput, Patch-Clamp is the established method for intracellular measurements of the transmembrane potential. To address this problem, we have developed new biosensor-chips with micro-structured needle electrodes (MNEs). MNE-penetration of single cells growing on the MNE-tips leads to a situation comparable to the whole-cell mode in classical Patch Clamp. MNE-penetration ...
E. R. Blatchley, and B.Z. Sun
Department of Civil Engineering, Purdue University, West Lafayette, IN, USA
Mineral precipitation on to the quartz surface of the lamp jackets in UV disinfection process (fouling) has been recognized as a major problem for UV radiation delivery during disinfection operation. Fouling behavior was observed to be induced thermally and influenced by hydraulic character of the UV disinfection configuration. Fouling process involves momentum, heat, and mass transport within ...
G. Demésy, F. Zolla, A. Nicolet, and M. Commandré
Institut Fresnel, Université Aix-Marseille III, École Centrale de Marseille, France
We demonstrate the accuracy of the Finite Element Method (FEM) to characterize an arbitrarily shaped crossed-grating in a multilayered stack illuminated by an arbitrarily polarized plane wave under oblique incidence. To our knowledge, this is the first time that 3D diffraction efficiencies are calculated using the FEM. The method has been validated using classical cases found in the literature. ...
COMSOL Multiphysics® as a Tool for Reducing Animals in Biomedical Research: An Application in Dermatology
F. Rossi and R. Pini
Istituto di Fisica Applicata “Nello Carrara”, Consiglio Nazionale delle Ricerche, Firenze, Italy
In biomedical research the use of animal models gives rise to several ethical problems. COMSOL Multiphysics® may be used as a non-animal technique, very useful in overcoming all these concerns. In this presentation a particular application in dermatology is shown. Bioheat equation mode and diffusion approximation were used to design a theoretical model of blue LED light interaction with an ...
Dependence of Potential and Ion Distribution on Electrokinetic Radius in Infinite and Finite-length Nano-channels
J. Schiffbauer, J. Fernandez, W. Booth, K. Kelly, A. Timperman, and B. Edwards
Physics Dept. West Virginia University, Morgantown, WV, USA
Chemical Engineering Dept,West Virginia University, Morgantown, WV, USA
Dept. of Chemistry, West Virginia University, Morgantown, WV, USA
A site-binding/dissociation model is used to determine surface charge in numerical studies of the equilibrium potential and ion distributions inside infinite and finite-length nano-channels. This COMSOL model allows us to investigate the response of surface (zeta) potential to environmental parameters such as reservoir salt concentration, solution pH and wall separation. The resulting ion and ...